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By J. W. Hadden (Eds.)

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1985) and the f i r i n g r a t e o f h y p o t h a l a m i c n e u r o n s i s a l t e r e d d u r i n g an immune r e s p o n s e ( B e s e d o v s k y , e t a l . , 1977). F u r t h e r m o r e , l y m p h o c y t e s a r e known t o p o s s e s s b e t a - 2 a d r e n e r g i c r e c e p ­ t o r s as well as other n e u r o t r a n s m i t t e r r e c e p t o r s ( F e i t e n , et a l . , 1 9 8 5 ) . A s e c o n d means f o r i n t e r a c t i o n s b e t w e e n m i n d a n d immune s y s t e m i n v o l v e s h o r m o n a l i n f l u e n c e s o n immune f u n c t i o n .

Cell Effect of r-IL-2 administration on lymphocyte subsets in rat peripheral blood 2 4 6 8 10 12 Weeks P e r i o d of r-IL2 a d m i n i s t r a t i o n declined to the predose level by the end of the study. In addition, considerable eosinophilia was particularly observed at the end of the study and monocytosis was found at a dose of 25 yg/kg/day during the dosing period. Analysis of lymphocyte subsets in peripheral blood was conducted by a flow cytofluorography using EPICS-V after labeling lymphocyte subsets with the corresponding monoclonal antibodies.

Pharmacology. 29> 31-39. , S. Y. Feiten, S. L. Carlson, D . L. Bellinger and D . L. Feiten (1985). Involvement of peripheral and central Overview on Neuroimmunomodulation 45 catecholamine systems in neural-immune interactions. J. Neuroi m m u n o l . , 1 0 , 5-30. , 0 . Kadlecová and P. Petrovicky (1985). The involvement of brain structures in the adjuvant effect of muramyl dipeptide. , 15. 4 4 3 - 4 6 6 . Masek, K. and 0 . Kadlecová (1987). Muramyl peptides, serotonergic system and sleep. Ann.

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