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Williams, M. , Fielding, C. , and Havel, R. J. (1976). J. Clin. Invest. 58, 667. Havel, R. , Shore, V. , and Bier, D. M. (1972). Circulation 27, 595. Havel, R. J. (1957). / . Clin. Invest. 36, 848. Havel, R. , Eder, H.

Sniderman and associates (1978) measured the difference in lipoprotein concentrations be­ tween aorta and hepatic veins in a large number of human subjects, as a means of determining the extraction of lipoproteins by the splanchnic bed. Although minute changes would not have been detectable, they found no significant arteriovenous difference in HDL cholesterol. By contrast LDL appeared to lose cholesterol and gain triglyceride. Schwartz et al. (1978) ad­ ministered HDL and LDL containing labeled free cholesterol to a patient with a bile fistula and showed that radioactivity appeared in bile more rapidly following HDL injection.

Atherosclerosis 21, 417. Carlson, L. , and Ericsson, M. (1975b). Atherosclerosis 21, 435. CasteUi, W. , Cooper, G. , et al. (1977a). J. Chron. Dis. 30, 147. Castelli, W. , Doyle, J. , Hames, C. , Hjortland, M. C , Hulley, S. , and Zukel, W. J. (1977b). Circulation 55, 767. Castelli, W. , Hjortland, M. , Doyle, J. , Hames, C. , Hulley, S. , and Zukel, W. J. (1977c). Lancet 2, 152. , and Eisenberg, S. (1978). J. Clin. Invest. 62, 1654. Cheung, M. C , and Albers, J. J. (1977). J. Clin. Invest. 60, 43.

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